Tess De Bruyne guest lecturer - senior researcher - project coordinator

Research Tess De Bruyne

Research team

Support maintenance scientific equipment. 01/01/2005 - 31/12/2005

Abstract

Researcher(s)

Funding

  • BOF
  • BELSPO

Project type(s)

  • Research Project

Structure-activity relationship investigation in correlation with bioavailability of proanthocyanidins as nutritional antioxidants. 01/01/2003 - 31/12/2006

Abstract

Researcher(s)

  • Promoter: Vlietinck Arnold
  • Co-promoter: De Bruyne Tess
  • Co-promoter: Vanden Berghe Dirk

Funding

  • FWO

Project type(s)

  • Research Project

01/05/2002 - 30/04/2004

Abstract

Researcher(s)

Funding

  • VLAIO

Project type(s)

  • Research Project

High pressure liquid chromatographic techniques with fluorimetric detection for the evaluation of antioxidative parameters in vivo and structure-activity assessment of antioxidative natural products. 01/01/2001 - 31/12/2003

Abstract

This project covers the assessment of the in vivo antioxidative properties of natural products. In a first step, rats are stressed with CCl4, after which the concentration of free malondialdehyde and related hydroxyalkenals, determined by means of HPLC, of stressed laboratory animals is compared to the normal, basal concentration. The use of fluorimetric detection enhances both sensitivity and selectivity of the method substantially, important parameters when using small laboratory animals with low MDA plasma concentrations. Subsequently, the in vivo antioxidative effect of some selected polyphenols will be determined, with emphasis on flavonoids and proanthocyanidins. For those compounds structure-activity relationships for in vivo inhibition of lipid peroxidation will be investigated.

Researcher(s)

Funding

  • FWO

Project type(s)

  • Research Project

Structure elucidation of biologically active natural products as prototypes for new drugs. 01/10/1999 - 30/09/2003

Abstract

Biologically active natural products from higher plants are isolated and identified, to serve as prototypes for potential new drugs.

Researcher(s)

Funding

  • FWO

Project type(s)

  • Research Project

Structure elucidation of biologically active natural products as prototypes for new drugs. 01/10/1996 - 30/09/1999

Abstract

Biologically active natural products from higher plants are isolated and identified, to serve as prototypes for potential new drugs.

Researcher(s)

Funding

  • FWO

Project type(s)

  • Research Project

Chromatographic and structural investigations of ì chemotherapeutically active plant phenolicsì 01/10/1991 - 30/09/1993

Abstract

The structure of chemotherapeutically active plant condensed tannins viz. dimeric and trimeric procyanidines of the A, B and C-series will be determined by means of two dimensional nuclear magnetic resonance (2-D-NMR) spectrometry

Researcher(s)

Funding

  • FWO

Project type(s)

  • Research Project

Chromatographic and structural investigations of ì chemotherapeutically active plant phenolicsì 01/10/1989 - 30/09/1991

Abstract

The structure of chemotherapeutically active plant condensed tannins viz. dimeric and trimeric procyanidines of the A, B and C-series will be determined by means of two dimensional nuclear magnetic resonance (2-D-NMR) spectrometry

Researcher(s)

Funding

  • FWO

Project type(s)

  • Research Project