The simplest method yet for ultrafast desalting of proteins and oligonucleotides in native mass spectrometry

Source
Analytical chemistry - ISSN 0003-2700-98:5 (2026) p. 3723-3731
Author(s)
    Edvaldo V.S. Maciel, Jonathan Eisert, Christian Hake, Alexander Schiesser, Frederik Lermyte

Introducing a CATALYST to accelerate native affinity selection mass spectrometry

Source
Journal of the American Society for Mass Spectrometry - ISSN 1044-0305-37:2 (2026) p. 396-406
Author(s)
    Jonathan Eisert, Edvaldo Vasconcelos Soares Maciel, Roman Grigoriev, Ilie Victor Hurbean, Leonard Kuhl, Luca Panholzer, Katharina Speh, Frederik Lermyte

Toward anti-herpesviral PROTACs : assessing the challenges for targeted protein degradation on the example of Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen

Source
ChemMedChem - ISSN 1860-7179-21:1 (2026) p. 1-13
Author(s)
    Aylin Berwanger, Saskia Catherina Stein, Sarah Brandner, Andreas Martin Kany, Sebastian Heinz, Brigitta Loretz, Claus-michael Lehr, Anna Katharina Herta Hirsch, Frederik Lermyte, Thomas Friedrich Schulz, Martin Empting

Native Taylor/non-Taylor dispersion-mass spectrometry (TNT-MS) allows rapid protein desalting and multiplexed, label-free ligand screening

Source
Small methods - ISSN 2366-9608-10:2 (2026) p. 1-10
Author(s)
    Jonathan Eisert, Edvaldo Vasconcelos Soares Maciel, Verena Dederer, Aylin Berwanger, Henry J. Bailey, Ivan Dikic, Stefan Knapp, Martin Empting, Sebastian Mathea, Henrik Jensen, Frederik Lermyte

Measuring the hydrodynamic radii of peptides and proteins with an unmodified LC-ESI-MS instrument operating in a Taylor dispersion regime

Source
The analyst - ISSN 0003-2654-150:13 (2025) p. 2829-2836
Author(s)
    Jonathan Eisert, Edvaldo Vasconcelos Soares Maciel, Henrik Jensen, Frederik Lermyte